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Iranian Researcher Makes Bionic Lenses
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A researcher holding one of the completed contact lenses.
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Babak Parviz wears contact lenses. But he’s not yet using the new contact lenses he’s made in his Seattle laboratory. Containing electronic circuits, they look like something from a science fiction movie.
According to the Guardian, the Iranian scientist and researcher of the University of Washington is now going to add some extremely small light emitting diodes (LEDs) to help turn his prototype contact lenses into a sophisticated personal display--the tiniest one possible.
As an assistant professor of electrical engineering at the University of Washington, Parviz works on bio-nanotechnology, self-assembly, nanofabrication and micro-electro mechanical systems. He makes tiny but functional electronic devices and, using nanotechnology and microfabrication techniques, integrates them on to polymers or glass using a process known as self-assembly.
So how did he think of making a ’bionic’ contact lens? “Imagine a person with that kind of research expertise and background,“ says Parviz. “Imagine also the same person waking up every morning and putting a contact lens in his eye.“
Making the connection wasn’t hard, as Parviz had also been thinking about unconventional displays. Contact lenses are made from flexible transparent polymers, just the sort of challenging material that Parviz likes to stick tiny electronic circuits on. “The driver is not to make something small. The driver is to make something that’s cool and useful. Having a display in a contact lens is very useful.“
Parviz argues that ironically, the current display sizes in mobile computers and phones hinder rather than help miniaturization. “The display size is one of the main reasons that laptops, cell phones, PDAs, etc are not smaller today. If we move the display to a contact lens, we can significantly remove the physical constraints on mobile devices.“
So far, he’s shown that high-performance circuitry, including microLEDs can be incorporated on to transparent, thin, flexible plastic substrates. The circuits involve making metal layers a few nanometers thick linked to LEDs that are about one third of a millimeter across. A microfabrication technique known as self-assembly relies on capillary effects to bring together pre-shaped pieces of circuit. The prototype contact lens--which will eventually contain LEDs--has yet to be powered up. That key step, says Parviz, is several months off.
2 Power Options
“We’re looking at two different ways to transmit power. One is radio frequency power transmission. We need antennae on these contact lenses anyway because we need to transmit data to them. The other way we’re looking at right now is to incorporate photovoltaic [solar] cells.“
Power isn’t the hardest problem. A contact lens sits directly on the surface of the eye, much too close for the eye’s lens to focus on. “To create the focused image we have to manipulate the light rays,“ says Parviz. “You can create a focused image if you use laser instead of LEDs.“
If shining very low power diode lasers on to the retina seems risky, then microLEDs might be the answer. These provide diffuse light and, to make them work, Parviz might integrate an array of individual micro-lenses into the contact lens. “If the pixel [the microLED] is close enough to the micro-lens, it will generate a virtual image that could be 30cm or more away from the surface. Our eyes can focus on this now.“
All this raises questions of biocompatibility: the electronics in the contact lenses must not harm the eye. If that’s assured, then the idea of a fully functional wireless display on a contact lens might seem, at first, to have many uses.
Parviz talks about augmented reality, such as superimposing text messages or direction arrows on your view of the world. But even trivial applications will require a high-resolution display. So his next step is to demonstrate a programmable wireless contact lens with a few pixels--perhaps eight--that’s safe to wear.
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High-Tech Sensor Being Developed
Scientists at the University of Southampton’s School of Electronics and Computer Science (ECS) are developing the world’s smallest, high-performance and low-power sensor in silicon which will have applications in biosensing and environmental monitoring.
Professor Hiroshi Mizuta and his team at ECS are part of the three year European FP7-funded NEMSIC (Nano-electro-mechanical-system-integrated-circuits) project which will make these devices possible, ScienceDaily wrote.
As well as being the smallest sensor on the market to date, it will have extreme sensitivity and very low power consumption. It will achieve this by co-integrating single-electron transistors (SETs) and nano-electro-mechanical systems (NEMS) on a common silicon technology platform.
“Power consumption is a big issue at the moment as devices use current whether they are switched off and on“ said Professor Mizuta. “The single-electron transistor combined with the NEM device technology reduces power consumption at both ON and OFF states of the sensor. Standby power is reduced to zero by having a complete sleep with the NEM switch when it is off.“
Professor Mizuta and his team will develop the single-electron transistor with a unique suspended silicon nanobridge which will work as an extremely sensitive detector for biological and chemical molecules.
“This is the first time that anyone has combined these two nanotechnologies to develop a smart sensor,“ said Professor Mizuta. “The traditional CMOS (Complementary metal-oxide-semiconductor) approach has many limitations so we needed to find a new approach.“ The sensing devices will need to be made to the nanoscale, which will be made possible by the new electron beam lithography machine which will be available in the new ECS Mountbatten building when it opens in July.
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Eczema Treatment Could
Help Prevent Asthma
More aggressive treatment of childhood eczema may be an important step in preventing asthma, says a new Australian study.
The study calls for trials of aggressive therapies against childhood eczema in an attempt to reduce the incidence of asthma in later life, ScienceDaily reported.
The study, conducted by the University of Melbourne, Monash University and Menzies Research Institute in Tasmania, has followed more than 8,500 people who are part of the Tasmanian Longitudinal Health Study from the ages of seven to 44.
Lead author John Burgess, from the University of Melbourne’s Melbourne School of Population Health, says the study is the first to demonstrate an association between childhood eczema and asthma into middle age.
The study found people who had childhood eczema were more likely to develop childhood asthma, new-onset asthma later in life or to have asthma which persisted from childhood into middle age.
Dr. Burgess said childhood eczema increased the risk of someone developing asthma well into adulthood.
“The incidence of asthma in people from the ages of 8 to 44 who had childhood eczema, was nearly double that of people who had never had eczema,“ Dr. Burgess said.
“The results of our study showed childhood eczema clearly preceded asthma in each later stage of life--later childhood, adolescence and adulthood,“ he said.
“This makes a strong argument for trialing aggressive therapies against childhood eczema to help reduce the burden of asthma later in life.“
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Vitamin A Benefit
A single, oral dose of vitamin A, given to infants shortly after birth in the developing world can reduce their risk of death by 15 percent, according to a new study.
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Serbian Scientist Makes Lab Blood
A daily reported on Saturday that geneticist Miodrag Stojkovic made “a sensational scientific discovery“ by producing “lab blood“.
Belgrade’s Vecernje Novosti daily said that this could represent a huge step forward in the treatment of many illnesses, including leukemia.
Leskovac-based Stojkovic, who spent much of his career in the United Kingdom, said that he experimented with embryo stem cells, to have them produce blood cells.
“The separation of blood stem cells from the human embryo makes it possible to produce an unlimited quantity of blood,“ he was quoted as saying.
Stojkovic added embryo stem cells can be used to produce 220 different types of human cells.
He pointed out that he had assistance from his colleagues based in Newcastle, UK, when he managed to make stem cells produce blood cells.
Syrup Prevents Childhood Caries
Dental researchers at the University of Washington have reported a significant reduction of tooth decay in toddlers who were treated with the topical syrup xylitol, a naturally occurring non-cavity-causing sweetener.
In a recent clinical trial in the Republic of the Marshall Islands, children 6 to 15 months old were given oral doses of xylitol in fruit-flavored syrup daily to determine whether the substance can prevent early-childhood tooth decay, or ’caries’ ScienceDaily reported.
Researchers announced that nearly 76 percent of the children in the group who received xylitol were free of tooth decay by the end of the study, compared with 48 percent of the children in the group that did not receive the substance.
The Marshall Islands in the Pacific were chosen for the study because it is an area where childhood tooth decay is a serious public health problem. The average child entering Head Start at age 5 has 6.8 cavities--two to three times the rate in a typical mainland community.
Xylitol can be administered in the form of chewing gum, lozenges, or syrup. According to researchers, at the end of the trial nearly 76 percent of the children in the study group were caries-free, compared with 48 percent in a comparable group that did not receive treatment.
Xylitol is a five-carbon sugar alcohol that is used as a sugar substitute.
New Navigation System Monitors Traffic
Researchers are developing a new in-car navigation system which informs motorists about traffic jams ahead and advises the driver of the best route for their journey before they reach the congestion.
The “Congestion Avoidance Dynamic Routing Engine“ (CADRE) uses Artificial Intelligence (AI) to interpret live traffic information shared between vehicles fitted with a special global positioning system (GPS), ScienceDaily said.
The project is part of a consortium, consisting of the University of Portsmouth, ComSine, Smartcom Software, the Transport Research Laboratory, ViaMichelin and Hampshire County Council.
CADRE can sense traffic slowing down and building up into jams and works by ’monitoring’ other vehicles on the road, informing motorists 5 to 10 miles away of a situation as it’s happening and recommends steps to avoid it while they can.
The AI software is built around “fuzzy logic“ which mimics human reasoning. The capability comes from the University of Portsmouth’s Institute of Industrial Research (IIR) which specializes in using artificial intelligence techniques for industrial applications.
Famished Gene May Help Cure Obesity
A genetic change that makes white people feel famished has been found in research that could help predict the children at risk of obesity and develop new treatments.
According to Telegraph, the common DNA mutation was found in people of European ancestry and the findings reveal that a minor change can have a significant impact on the production of several hormones controlling our appetite, which scientists say is “definite evidence that common obesity is a disease of the appetite and satiety“.
The mutation, each copy of which raises the risk of obesity by 50 percent, is found in around one person in every four white people, according to research published today in Nature Genetics by an international team led by Imperial College London.
Understanding this mechanism will help scientists to develop new treatments, notably by making obese people feel full.
The gene, called PCSK1, is the recipe for the body to make the “proconvertase enzyme“, which is responsible for producing fully functioning versions of hormones such as insulin, glugagon and melanocortin. These are all involved in controlling the rate of metabolism.
Changes in the PCSK1 gene cause relatively minor abnormalities in the enzyme that can have a major effect on the way the body responds to the hormones, which all play a major role in regulating weight.
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