1148 GMT March 31, 2020
Six years in the making, the international commitment could prevent 700,000 deaths a year, say experts, BBC reported.
It is the fourth time a UN declaration has been reached on a health issue — following HIV in 2001, non-communicable diseases in 2011 and Ebola in 2013.
The signatories now have two years to report back with an action plan.
Experts say treatment-resistant infections pose one of the biggest known threats to humanity today.
Without urgent action, it is conceivable that simple infections could soon become entirely untreatable with existing drugs.
The problem has been caused by over-use of antimicrobial medicines for humans, animals and agriculture.
Repeated exposure allows bacteria and other infections, including HIV and malaria, to learn how to dodge these treatments by mutating and evolving.
Unless new effective treatments are found, routine medical procedures such as hip operations and Caesarean sections could become too dangerous to perform.
The nations have committed to: