Gaza's Health Ministry spokesman, Ashraf al-Qidra, said the four Palestinians were moderately injured when Israeli fighter jets struck Nahda neighborhood of the border town of Rafah on Monday afternoon, Press TV quoted Arabic-language Quds Press news agency as reporting.
Witnesses, speaking on condition of anonymity, said Israeli fighter jets had also fired two missiles at a military site belonging to the Hamas resistance movement, west of Nuseirat refugee camp just after 1 p.m. local time (1100 GMT).
Reuters quoted the Israeli military as saying that its planes attacked five positions belonging to Hamas.
According to Press TV, an Israeli unmanned aerial vehicle fired a missile at a monitoring post east of Rafah as well, with no immediate reports of casualties or damage.
Shortly afterward, Israeli warplanes launched three missiles at Hitteen outpost in the city of Beit Lahia, located about five kilometers north of Gaza City.
The airstrikes came shortly after the Israeli military claimed that a rocket fired from the Gaza Strip had hit an open area in southern occupied territories, but caused no injuries or damage.
The Israeli military frequently bombs the Gaza Strip, with civilians being the main target of such attacks.
On February 9, Israeli warplanes targeted a lifeline tunnel in Rafah, leaving two Palestinians dead and five others injured. Gazans use the tunnels to bring basic commodities into the coastal enclave.
The Gaza Strip has been under an Israeli siege since June 2007. The blockade has caused a decline in living standards as well as unprecedented unemployment and poverty.
Two Palestinians were also injured on February 6, when Israeli warplanes struck a farming land in the center of Khan Yunis city, located about 25 kilometers south of Gaza City.
Israel has also launched several wars on the Palestinian sliver, the last of which began in early July 2014. The 50-day military aggression, which ended on August 26, 2014, killed nearly 2,200 Palestinians. Over 11,100 others were also wounded in the war.