0209 GMT March 22, 2018
The Amtrak train -- Train 91 -- traveling between New York and Miami derailed in Cayce, outside the state capital Columbia, in the collision with the CSX freight train, which took place at around 2:30 am (0730 GMT).
Amtrak, the national US railway service, said in a statement that the lead engine derailed along with some passenger cars. Eight crew members and 139 passengers were on board.
US media reported injuries ranged from cuts and bruises to broken bones.
The Lexington County Sheriff's Department confirmed all passengers had been evacuated. The local Red Cross opened a shelter in a school to help passengers.