0121 GMT January 20, 2019
Iranian researchers produced laboratory samples of a type of electrochemical nanobiosensor capable of analyzing individuals’ blood samples and detecting breast cancer.
Early detection of breast cancer in individuals is of great assistance in employing suitable treatment methods and techniques and helping patients live longer, IRNA reported.
A subgroup of breast cancer is Triple Negative Breast Cancer (TNBC). Between 15 percent and 20 percent of the individuals suffering from breast cancer are diagnosed to have developed TNBC which is the most invasive form of this cancer.
One of the researchers of the project to produce the sensor, Dr. Elahe Bozrogzadeh, said given that patients suffering from TNBC do not respond to common hormonal treatments, this type of cancer is required to be detected as soon as possible and in the early stages of its development.
Bozrogzadeh, who is a researcher at Gilan University of Medical Sciences, added to eliminate the high costs involved in undergoing the ineffective hormonotherapy in patients suffering from TNBC, early detection of this type of cancer in individuals help them receive suitable treatments as soon as possible.
She said it appears that one of the most important steps in early detection and, thus, treatment of this type of cancer is using certain biomarkers, which is a precise method for diagnosing it and measuring its intensity precisely.
“Given the importance of this issue, we began a study to devise an electrochemical nanobiosensor to measure the biomarker specific to this type of cancer in individual’s [blood] serum.”
She added that among the most important steps in detecting different kinds of cancer in patients is using certain biomarkers, such as ‘miRNA’ and measuring them.
The researcher noted that ‘miR-199a-5p’ is the biomarker used in detecting TNBC.
She said the results of their study shows that the electrochemical nanobiosensor they have designed has high sensitivity and precision in identifying and measuring ‘MiR-199a-5p’ biomarker.
Bozrogzadeh added using this nanobiosensor is a non-invasive method for detecting cancer and has no side effects.