Ashraf al-Qedra, the spokesman for the Gaza Health Ministry, said Aml Moustafa Ahmed, 43, was killed by Israeli fire during protests east of the Gaza Strip on Friday.
He added that the Israeli forces also shot and wounded at least 25 other people during the clashes. Two journalists and a paramedic were also injured after they were hit by tear gas bombs, Presstv Reported.
Tensions have been running high near the fence separating Gaza from the occupied territories since March 30, which marked the start of the protests.
Palestinian protesters demand the right to return for those driven out of their homeland.
The clashes in Gaza reached their peak on May 14, the eve of the 70th anniversary of Nakba Day, or the Day of Catastrophe, which coincided this year with Washington's relocation of the US embassy from Tel Aviv to occupied Jerusalem al-Quds.
More than 240 Palestinians have so far been killed and over 20,000 others wounded in the renewed Gaza clashes, according to the latest figures released by the Gaza Health Ministry.
Gaza has been under Israeli siege since June 2007, causing a decline in living standards as well as unprecedented unemployment and poverty.
Separately, the Palestinian Health Ministry in the occupied West Bank announced that Israeli forces seriously injured a Palestinian man in the city of al-Khalil (Hebron) on Friday.
The Israeli military had claimed that the man was trying to stab Israeli soldiers near Kiryat Arba settlement.
About 600,000 Israelis live in over 230 illegal settlements built since the 1967 Israeli occupation of the Palestinian territories of the West Bank and East Jerusalem al-Quds.
Palestinians want the West Bank as part of a future independent Palestinian state with East Jerusalem al-Quds as its capital.
The last round of Israeli-Palestinian talks collapsed in 2014. Among the major sticking points in those negotiations was Israel’s continued settlement expansion on Palestinian territories.
The ministry’s brief statement came after initial reports said that the man was killed.
The Israeli military regularly opens fatal fire on Palestinians, accusing them of seeking to attack its personnel.