Juventus players leave the pitch in frustration after their team suffered a first league defeat of the season against Genoa at Stadio Comunale Luigi Ferraris, Genoa, Italy, on March 17, 2019.
Ronaldo missed the trip to Genoa after firing the Serie A side to the Champions League quarterfinals with a hat-trick over Atletico Madrid during the week, AFP reported.
Sturaro and Pandev came off the bench in the second half scoring on 72 minutes and 81 minutes respectively to inflict the first league defeat on Massimiliano Allegri's side since April 2018 against Napoli.
The Champion had already been beaten this season by Atalanta in the Coppa Italia and lost in the Champions League to Manchester United and Young Boys in the group stage and Atletico Madrid the last 16 first leg.
Juventus had won 24 of its 27 previous matches in Serie A with three draws including 1-1 to Genoa in the reverse fixture.
Allegri's side remains on track for an eighth consecutive title as it sited 18 points clear of second-placed Napoli before Carlo Ancelotti’s men hosted Udinese later on Sunday.
Genoa moved up to 12th after this eighth win of the season.