City's chief operating officer, Omar Berrada, described the comments as "curious" after Klopp grouped the Citizens with Barcelona, Real Madrid and Paris Saint-Germain in terms of sustained squad investment, goal.com reported.
"It looks like there are four clubs in the world who can do it constantly. Madrid, Barcelona, City and PSG. You cannot compare that," the German said earlier this week.
Liverpool has signed two teenagers – Sepp van den Berg and Harvey Elliott – since winning the Champions League, while City broke its club-record fee to secure midfielder Rodri from Atletico Madrid.
Pep Guardiola has suggested he would like to bring in another defender at Etihad Stadium before the August 8 deadline, but Klopp is unlikely to add any extra recruits at Anfield.
"We were a little bit surprised," Berrada said.
"Liverpool are a great sporting rival.
"I don't know why they would make these comments. I don't know why they would look at other clubs. It's not frustration or anger, we just find it curious that they'd be highlighting our spending.
"We're fine with their spending. The reality is that all the top clubs invest as they see fit.
"Saying us, PSG, Real Madrid and Barcelona always invest £200 million is not correct. We don't look at what others do."
Liverpool itself spent over £100 million ($121 million) on Alisson, Fabinho and Xherdan Shaqiri prior to the start of last season, which saw the Reds finish as runners-up to City in the Premier League.
Guardiola's side successfully defended its crown by the narrowest of margins, while also winning the Carabao Cup and FA Cup to complete an unprecedented treble.
The two clubs face each other in the Community Shield on Sunday, with the 2019-20 campaign set to kick off five days later.
The curtain raiser will see Liverpool host newly-promoted Norwich at Anfield, with City set to open its season with a trip to West Ham on August 10.