A team of researchers at VIB and KU Leuven has uncovered why people with a hereditary form of Parkinson's disease suffer from sleep disturbances. The molecular mechanisms uncovered in fruit flies and human stem cells also point to candidate targets for the development of new treatments.
A collaborative team of researchers at McLean Hospital, a Harvard Medical School affiliate, and Oxford University has found that elevated levels of certain types of lipids (fat molecules) in the brain may be an early sign of Parkinson's disease (PD).
Northwestern Medicine investigators have discovered how a gene mutation results in buildup of a toxic compound known to cause Parkinson's disease symptoms, defining for the first time the mechanism underlying that aspect of the disease.
Security images inviting users to type words, or click on pictures, to prove they are ‘not a robot’ are undoubtedly frustrating for many. But scientists have discovered that some people with Parkinson’s disease struggle more than most at the task, and it could point to important changes happening in the brain.
People with Parkinson's disease are about four times more likely to develop melanoma skin cancer and conversely, people with melanoma have a fourfold higher risk of getting Parkinson's, researchers report.
Exposure to a group of common pesticides, called dithiocarbamates, has long been associated with an increased risk of Parkinson's disease, although the mechanism by which the compounds exert their toxicity on the brain has not been completely understood.
Brazilian researchers at D'OR Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ) have taken what they describe as an important step toward using the implantation of stem cell-generated neurons as a treatment for Parkinson's disease.
A new study, published online in Brain: A Journal of Neurology, followed 43,368 individuals in Sweden for an average of 12.6 years to examine the impact of physical activity on Parkinson's disease risk. It was found that "a medium amount" of physical activity lowers the risk of Parkinson's disease.